Heme/Onc Testing:

Chronic Myeloid Leukemia (CML)

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  • BCR/ABL1 is the primary gene rearrangement associated with Chronic Myeloid Leukemia (CML), resulting from a translocation between chromosomes 9 and 22.

  • This rearrangement creates a protein that drives cellular growth out of control and leads to overproduction of certain blood cells.

  • FISH for BCR/ABL1 allows the translocation to be identified at diagnosis and monitored for disease progression or relapse.

FISH Testing
Turnaround Time = 3-5 Days

Cytogenetic Testing
Turnaround Time = 7 Days or Less

 
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